Assessment and Therapeutic Modulation of Heart Rate Variability: Potential Implications in Patients with COVID-19

نویسندگان

چکیده

Cardiac damage has been attributed to SARS-CoV-2-related pathology contributing increased risk of vascular events. Heart rate variability (HRV) is a parameter functional neurocardiac integrity with low HRV constituting an independent predictor cardiovascular mortality. Whether structural cardiac translates into dysfunction in patients infected SARS-CoV-2 remains poorly understood. Hypothesized mechanisms possible COVID-19 comprise direct systemic neuroinvasion autonomic control centers, ascending virus propagation along cranial nerves and neuropathy. While the relationship between nervous system cytokine cascade general studied extensively, interplay inflammatory response caused by regulation largely unclear. We reviewed current literature on potential diagnostic prognostic value function assessment via analysis including time domain spectral techniques COVID-19. Furthermore, we discuss therapeutic targets modulating this high-risk population biofeedback impact long COVID as well approaches clinical management. These topics might be particular interest respect multimodal pandemic preparedness concepts.

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Development and Disease

سال: 2023

ISSN: ['2308-3425']

DOI: https://doi.org/10.3390/jcdd10070297